Session 2-1: Enzymatic and Catalytic Deconstruction

Keywords: enzyme discovery, engineering, and synergy. Mechanisms and modeling of enzymatic deconstruction of bio-based feedstocks

Enzymes and chemical catalysis are central to production of fuels and chemicals from renewable plant-based feedstocks, whether through direct deconstruction of lignocellulose or conversion of biomass-derived components to useful monomers and feedstock chemicals. Non-exclusive topics include:


Anne Stenbæk – Novozymes-Denmark
Igor Polikarpov – USP

  • Enzyme discovery, engineering, and synergy
  • Biomass deconstruction through homogeneous and heterogeneous catalysis
  • Mechanisms and modeling of enzymatic or catalytic deconstruction of bio-based feedstocks

Session 2-2: Physical, Thermal, and Chemical Deconstruction

Keywords: biomass pretreatment, catalytic deconstruction, engineering operations in biomass processing

Pretreatment is an essential component of biomass processing and spans a range of technologies and methods. Mechanical and thermal energy, as well as chemically-mediated bond disruption are all potentially useful in reducing lignocellulosic biomass to readily deconstructable subcomponents. These methods are also useful in direct conversion of biomass to products such as bio-oil and syn-gas which can be further upgraded through catalysis. Non-exclusive topics include:


Venkatesh Balan – University of Houston
Blake Simmons – Berkely/JBEI

  • Biomass size-reduction, fractionation, pretreatment, recovery, separation, and processing
  • Upgrading of biomass-derived components via homogeneous and heterogeneous catalysis
  • Engineering operations in biomass processing

Session 2-3: Synthetic and Systems Biology

Keywords: yeast/fungal/bacterial synthetic and systems biology, cellular and metabolic modeling, consortia in bio-based products

Microbial, synthetic, and systems biology are major tools in both biomass deconstruction and upgrading and conversion of biomass-derived molecules. Research efforts range from broad development of microbial consortia to selection and engineering of specific strains down to metabolic pathway engineering for specific products or properties. Non-exclusive topics include:


Pirkko Suominen – Cargill
Yi Wang – Auburn

  • Yeast/fungal/bacterial synthetic or systems biology
  • Cellular and metabolic engineering
  • -omics approaches to understand microbial interactions with biomass and bioproduct formation
  • Consortia in bio-based products
  • Microbial discovery and selection
  • Computational modeling of microbial communities, metagenomes, and cellular processes

Session 2-4: Enabling Analytical Technologies

Keywords: DOE/other user facilities (EMSL, JGI, synchrotrons and beamlines, etc.), HTP methods, advanced imaging and spectroscopy, real-time process monitoring, standarized analytical methods

Advanced analytics and high throughput screening technologies are essential for advancing biomass conversion research. Many of these efforts are greatly facilitated by various joint research and public user facilities, which often provide access to capabilities or capacities not available in single research groups. Non-exclusive topics include:


Carlos Driemeier – CTBE/CNPEM
Hugh O’Neill – ORNL

  • DOE/other user facilities (EMSL, JGI, synchrotrons and beamlines, etc.)
  • HTP and rapid-analysis methods development and application to biomass conversion
  • Advanced imaging and spectroscopy to understanding deconstruction processes and biomass structure and interactions with various deconstruction methods
  • Real-time process monitoring
  • Standardized analytical methods