This workshop is designed as an advanced course to deeply broaden the participants understanding of fermentation principles, especially related to industrial fermentations such as enzymes, biochemicals and probiotics. It is targeted to those with an established foundation regarding fermentation concepts.

The instructors have extensive practical industrial experience in process development and scale-up. As such, the intent will favor practical applications with specific examples vs a concentrated theoretical approach.

The workshop will build upon the basic concepts of fermentation and provide in depth examples of how the manipulation of these concepts impact fermentation. Overlapping methods that provide orthogonal verification of fermentation data will be emphasized across topics. The power of off-gas data to make process decisions will be stressed. Mixing, gas transfer and more complex temperature control predictions will be covered. Successful scale-up is one of the more challenging aspects of industrial fermentation and will be addressed with governing principles and real-world examples. Scale-down, taking processes back to the lab, can be equally challenging. It too will be addressed.

Who Should Attend?

For attendees who have an established foundation with fermentation concepts (2+ years of experience).

Attendees are invited to bring their own laptops but they are not required.

Onsite Fees (After 10/2/2023) – $750

Onsite Fees (After 10/2/2023) – $900

Registration Links

Register Online
Registration Form

Certificate of Attendance

A certificate of attendance is available after the completion of the workshop and by email request only. Please contact registrar@simbhq.org.

This workshop will present the recent advances in single-use techniques for microbial fermentation and cell culture from inoculation through harvest. Medium and sterilization techniques to simplify workflows and achieve high density cultures will be reviewed. Process analytical technology and monitoring options such as pH, DO, Temp, Raman, Off-gas analysis, and others will be presented. Various methods of control and feed strategies will be discussed to help end users with ideas on smoothing out control oscillation and improving expression.

Equivalent expression in single-use reactors vs. steel vessels in the same time frame is achievable with high-density cultures. In both cases harvest with filter or disk centrifuge methods present challenges for cleaning, processing time, and maintaining closed-system processes. Time saving advances in single-use systems to simplify closed-system production from inoculation through harvest will be discussed. Recent performance data will be shared from relevant application studies. Examples will be provided of how to further improve process productivity and reduce risks with the use of the medium with single-use fermentation systems and innovative feed strategies.

Who Should Attend?

Any level of experience with interest learning in single-use techniques for microbial cultures.

Attendees are invited to bring their own laptops but they are not required.

Onsite Fees (After 10/2/2023) – $750

Onsite Fees (After 10/2/2023) – $900

Registration Links

Register Online
Registration Form

Certificate of Attendance

A certificate of attendance is available after the completion of the workshop and by email request only. Please contact registrar@simbhq.org.